Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

Plasmacytoid dendritic cells (pDC) are specialized in secretion of type I interferon in response to pathogens. Here we show that natural monoamines and synthetic amines inhibit pDC activation by RNA viruses. Furthermore, a synthetic analogue of histamine reduces type I interferon production in a mou...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Smith, Nikaïa, Pietrancosta, Nicolas, Davidson, Sophia, Dutrieux, Jacques, Chauveau, Lise, Cutolo, Pasquale, Dy, Michel, Scott-Algara, Daniel, Manoury, Bénédicte, Zirafi, Onofrio, McCort-Tranchepain, Isabelle, Durroux, Thierry, Bachelerie, Françoise, Schwartz, Olivier, Münch, Jan, Wack, Andreas, Nisole, Sébastien, Herbeuval, Jean-Philippe
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309800/
https://ncbi.nlm.nih.gov/pubmed/28181493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14253
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker