Crosstalk of ROS/RNS and autophagy in silibinin-induced apoptosis of MCF-7 human breast cancer cells in vitro

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in regulating cell survival and death. Silibinin is a natural polyphenolic flavonoid isolated from milk thistle with anti-tumor activities, but it was found to induce cytoprotective ROS/RNS in human breast cancer...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Zheng, Nan, Liu, Lu, Liu, Wei-wei, Li, Fei, Hayashi, Toshihiko, Tashiro, Shin-ichi, Onodera, Satoshi, Ikejima, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309753/
https://ncbi.nlm.nih.gov/pubmed/27867187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.117
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