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Fibroblast Growth Factor-2 Suppresses Oridonin-Induced L929 Apoptosis Through Extracellular Signal-Regulated Kinase-Dependent and Phosphatidylinositol 3-Kinase-Independent Pathway

Oridonin, isolated from Rabdosia rubescences, has been reported to exert cytotoxic effects on L929 cells. In this study, we investigated the mechanisms of FGF-2 protection of L929 cells from oridonin-induced apoptosis. Phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signal did not mediat...

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Detalhes bibliográficos
Main Authors: Jian Huang, Lijun Wu, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2006-01-01
Colecção:Journal of Pharmacological Sciences
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1347861319343737
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