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The Biophysical Probes 2-fluorohistidine and 4-fluorohistidine: Spectroscopic Signatures and Molecular Properties

Fluorinated amino acids serve as valuable biological probes, by reporting on local protein structure and dynamics through (19)F NMR chemical shifts. 2-fluorohistidine and 4-fluorohistidine, studied here with DFT methods, have even more capabilities for biophysical studies, as their altered pK(a) val...

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Vydáno v:Sci Rep
Hlavní autoři: Kasireddy, Chandana, Ellis, Jonathan M., Bann, James G., Mitchell-Koch, Katie R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309746/
https://ncbi.nlm.nih.gov/pubmed/28198426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42651
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