Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells

Schwann cells (SCs) generate the myelin wrapping of peripheral nerve axons and are promising candidates for cell therapy. However, to date a renewable source of SCs is lacking. In this study, we show the conversion of skin fibroblasts into induced Schwann cells (iSCs) by driving the expression of tw...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mazzara, Pietro Giuseppe, Massimino, Luca, Pellegatta, Marta, Ronchi, Giulia, Ricca, Alessandra, Iannielli, Angelo, Giannelli, Serena Gea, Cursi, Marco, Cancellieri, Cinzia, Sessa, Alessandro, Del Carro, Ubaldo, Quattrini, Angelo, Geuna, Stefano, Gritti, Angela, Taveggia, Carla, Broccoli, Vania
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309703/
https://ncbi.nlm.nih.gov/pubmed/28169300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14088
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