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Flunarizine Rescues Reduced Lifespan in CLN3 Triple Knock-Out Caenorhabditis elegans Model of Batten Disease

CLN3 disease (Spielmeyer-Vogt-Sjogren-Batten disease, previously known as classic juvenile neuronal ceroid lipofuscinosis, NCL) is a pediatric-onset progressive neurodegenerative disease characterized by progressive vision loss, seizures, loss of cognitive and motor function, and early death. While...

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Bibliografische gegevens
Gepubliceerd in:J Inherit Metab Dis
Hoofdauteurs: Kwon, Young-Joon, Falk, Marni J., Bennett, Michael J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309197/
https://ncbi.nlm.nih.gov/pubmed/27766444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-016-9986-1
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