Actin Dynamics and Competition for Myosin Monomer Govern the Sequential Amplification of Myosin Filaments

Cellular mechanisms governing non-muscle myosin 2 (NM2) filament assembly are largely unknown. Using EGFP-NM2A knock-in fibroblasts and multiple super-resolution imaging modalities, we characterized and quantified the sequential amplification of NM2 filaments within lamella, wherein filaments emanat...

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Udgivet i:Nat Cell Biol
Main Authors: Beach, Jordan R., Bruun, Kyle S., Shao, Lin, Li, Dong, Swider, Zac, Remmert, Kirsten, Zhang, Yingfan, Conti, Mary A., Adelstein, Robert S., Rusan, Nasser M., Betzig, Eric, Hammer, John A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308804/
https://ncbi.nlm.nih.gov/pubmed/28114272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3463
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