Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

BACKGROUND: Glioblastomas (GBM) are the most common malignant type of primary brain tumor. GBM are intensively treated with surgery and combined radiochemotherapy using X-irradiation and temozolomide (TMZ) but they are still associated with an extremely poor prognosis, urging for the development of...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Riedel, Matthias, Struve, Nina, Müller-Goebel, Justus, Köcher, Sabrina, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai, Kriegs, Malte
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308705/
https://ncbi.nlm.nih.gov/pubmed/27542273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11328
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