Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial

BACKGROUND: The goal of this prospective multicentric trial was to validate a technique that allowed for MGMT promoter methylation analysis in routine clinical practice. METHODS: The MGMT status of 139 glioblastoma patients, whom had received standard first line treatment, was determined using pyros...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Quillien, Véronique, Lavenu, Audrey, Ducray, François, Joly, Marie-Odile, Chinot, Olivier, Fina, Frédéric, Sanson, Marc, Carpentier, Catherine, Karayan-Tapon, Lucie, Rivet, Pierre, Entz-Werle, Natacha, Legrain, Michèle, Zalcman, Emmanuèle Lechapt, Levallet, Guenaelle, Escande, Fabienne, Ramirez, Carole, Chiforeanu, Dan, Vauleon, Elodie, Figarella-Branger, Dominique
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308700/
https://ncbi.nlm.nih.gov/pubmed/27542245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11322
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