DGKI Methylation Status Modulates the Prognostic Value of MGMT in Glioblastoma Patients Treated with Combined Radio-Chemotherapy with Temozolomide

BACKGROUND: Consistently reported prognostic factors for glioblastoma (GBM) are age, extent of surgery, performance status, IDH1 mutational status, and MGMT promoter methylation status. We aimed to integrate biological and clinical prognostic factors into a nomogram intended to predict the survival...

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Detalhes bibliográficos
Main Authors: Etcheverry, Amandine, Aubry, Marc, Idbaih, Ahmed, Vauleon, Elodie, Marie, Yannick, Menei, Philippe, Boniface, Rachel, Figarella-Branger, Dominique, Karayan-Tapon, Lucie, Quillien, Veronique, Sanson, Marc, de Tayrac, Marie, Delattre, Jean-Yves, Mosser, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169423/
https://ncbi.nlm.nih.gov/pubmed/25233099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104455
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