Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

Ependymomas in children can arise throughout all compartments of the central nervous system (CNS). Highly malignant paediatric ependymoma subtypes are Group A tumours of the posterior fossa (PF-EPN-A) and RELA-fusion positive (ST-EPN-RELA) tumours in the supratentorial compartment. It was repeatedly...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Tzaridis, Theophilos, Milde, Till, Pajtler, Kristian W., Bender, Sebastian, Jones, David T. W., Müller, Simone, Wittmann, Andrea, Schlotter, Magdalena, Kulozik, Andreas E., Lichter, Peter, Collins, V. Peter, Witt, Olaf, Kool, Marcel, Korshunov, Andrey, Pfister, Stefan M., Witt, Hendrik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308696/
https://ncbi.nlm.nih.gov/pubmed/27556362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11452
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