Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

Ependymomas in children can arise throughout all compartments of the central nervous system (CNS). Highly malignant paediatric ependymoma subtypes are Group A tumours of the posterior fossa (PF-EPN-A) and RELA-fusion positive (ST-EPN-RELA) tumours in the supratentorial compartment. It was repeatedly...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tzaridis, Theophilos, Milde, Till, Pajtler, Kristian W., Bender, Sebastian, Jones, David T. W., Müller, Simone, Wittmann, Andrea, Schlotter, Magdalena, Kulozik, Andreas E., Lichter, Peter, Collins, V. Peter, Witt, Olaf, Kool, Marcel, Korshunov, Andrey, Pfister, Stefan M., Witt, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308696/
https://ncbi.nlm.nih.gov/pubmed/27556362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11452
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