Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

Ependymomas in children can arise throughout all compartments of the central nervous system (CNS). Highly malignant paediatric ependymoma subtypes are Group A tumours of the posterior fossa (PF-EPN-A) and RELA-fusion positive (ST-EPN-RELA) tumours in the supratentorial compartment. It was repeatedly...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Tzaridis, Theophilos, Milde, Till, Pajtler, Kristian W., Bender, Sebastian, Jones, David T. W., Müller, Simone, Wittmann, Andrea, Schlotter, Magdalena, Kulozik, Andreas E., Lichter, Peter, Collins, V. Peter, Witt, Olaf, Kool, Marcel, Korshunov, Andrey, Pfister, Stefan M., Witt, Hendrik
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308696/
https://ncbi.nlm.nih.gov/pubmed/27556362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11452
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