Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

Cardiac fibrosis is a common pathological process accompanying diabetes mellitus. In this report, we studied the effects of neferine (a major bisbenzylisoquinline alkaloid derived from lotus embryos) on cardiac fibrosis induced by diabetes mellitus, as well as the underlying molecular pathways. In v...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Liu, Xue, Song, Xiuhui, Lu, Jianjun, Chen, Xueying, Liang, Ershun, Liu, Xiaoqiong, Zhang, Mingxiang, Zhang, Yun, Du, Zhanhui, Zhao, Yuxia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308684/
https://ncbi.nlm.nih.gov/pubmed/27533252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11225
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