Neferine inhibits proliferation and collagen synthesis induced by high glucose in cardiac fibroblasts and reduces cardiac fibrosis in diabetic mice

Cardiac fibrosis is a common pathological process accompanying diabetes mellitus. In this report, we studied the effects of neferine (a major bisbenzylisoquinline alkaloid derived from lotus embryos) on cardiac fibrosis induced by diabetes mellitus, as well as the underlying molecular pathways. In v...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Liu, Xue, Song, Xiuhui, Lu, Jianjun, Chen, Xueying, Liang, Ershun, Liu, Xiaoqiong, Zhang, Mingxiang, Zhang, Yun, Du, Zhanhui, Zhao, Yuxia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308684/
https://ncbi.nlm.nih.gov/pubmed/27533252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11225
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