Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

Hepatitis C virus (HCV) can replicate in peripheral blood mononuclear cells (PBMCs), which can produce interferon to defend against virus infection. We hypothesized that dynamic gene expression in PBMCs might impact the treatment efficacy of peginterferon/ribavirin in HCV patients. PBMCs were collec...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Lu, Ming-Ying, Huang, Ching-I, Hsieh, Ming-Yen, Hsieh, Tusty-Juan, Hsi, Edward, Tsai, Pei-Chien, Tsai, Yi-Shan, Lin, Ching-Chih, Hsieh, Meng-Hsuan, Liang, Po-Cheng, Lin, Yi-Hung, Hou, Nai-Jen, Yeh, Ming-Lun, Huang, Chung-Feng, Lin, Zu-Yau, Chen, Shinn-Cherng, Huang, Jee-Fu, Chuang, Wan-Long, Dai, Chia-Yen, Yu, Ming-Lung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308654/
https://ncbi.nlm.nih.gov/pubmed/27542257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11348
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