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Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

Hepatitis C virus (HCV) can replicate in peripheral blood mononuclear cells (PBMCs), which can produce interferon to defend against virus infection. We hypothesized that dynamic gene expression in PBMCs might impact the treatment efficacy of peginterferon/ribavirin in HCV patients. PBMCs were collec...

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發表在:Oncotarget
Main Authors: Lu, Ming-Ying, Huang, Ching-I, Hsieh, Ming-Yen, Hsieh, Tusty-Juan, Hsi, Edward, Tsai, Pei-Chien, Tsai, Yi-Shan, Lin, Ching-Chih, Hsieh, Meng-Hsuan, Liang, Po-Cheng, Lin, Yi-Hung, Hou, Nai-Jen, Yeh, Ming-Lun, Huang, Chung-Feng, Lin, Zu-Yau, Chen, Shinn-Cherng, Huang, Jee-Fu, Chuang, Wan-Long, Dai, Chia-Yen, Yu, Ming-Lung
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308654/
https://ncbi.nlm.nih.gov/pubmed/27542257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11348
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