Dynamics of PBMC gene expression in hepatitis C virus genotype 1-infected patients during combined peginterferon/ribavirin therapy

Hepatitis C virus (HCV) can replicate in peripheral blood mononuclear cells (PBMCs), which can produce interferon to defend against virus infection. We hypothesized that dynamic gene expression in PBMCs might impact the treatment efficacy of peginterferon/ribavirin in HCV patients. PBMCs were collec...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Lu, Ming-Ying, Huang, Ching-I, Hsieh, Ming-Yen, Hsieh, Tusty-Juan, Hsi, Edward, Tsai, Pei-Chien, Tsai, Yi-Shan, Lin, Ching-Chih, Hsieh, Meng-Hsuan, Liang, Po-Cheng, Lin, Yi-Hung, Hou, Nai-Jen, Yeh, Ming-Lun, Huang, Chung-Feng, Lin, Zu-Yau, Chen, Shinn-Cherng, Huang, Jee-Fu, Chuang, Wan-Long, Dai, Chia-Yen, Yu, Ming-Lung
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308654/
https://ncbi.nlm.nih.gov/pubmed/27542257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11348
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