Exogenous IL-33 overcomes T cell tolerance in murine acute myeloid leukemia

Emerging studies suggest that dominant peripheral tolerance is a major mechanism of immune escape in disseminated leukemia. Using an established murine acute myeloid leukemia (AML) model, we here show that systemic administration of recombinant IL-33 dramatically inhibits the leukemia growth and pro...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qin, Lei, Dominguez, Donye, Chen, Siqi, Fan, Jie, Long, Alan, Zhang, Minghui, Fang, Deyu, Zhang, Yi, Kuzel, Timothy M., Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308636/
https://ncbi.nlm.nih.gov/pubmed/27517629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11179
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