Exogenous IL-33 restores dendritic cell activation and maturation in established cancer

The role of IL-33 particularly in tumor growth and tumor immunity remains ill defined. We show here that exogenous IL-33 can induce robust antitumor effect through a CD8(+) T cell-dependent mechanism. Systemic administration of recombinant IL-33 (rIL-33) alone was sufficient to inhibit growth of est...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Dominguez, Donye, Ye, Cong, Geng, Zhe, Chen, Siqi, Fan, Jie, Qin, Lei, Long, Alan, Wang, Long, Zhang, Zhuoli, Zhang, Yi, Fang, Deyu, Kuzel, Timothy M., Zhang, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263113/
https://ncbi.nlm.nih.gov/pubmed/28011934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501399
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