Role of mir-15a/16-1 in early B cell development in a mouse model of chronic lymphocytic leukemia

In both human chronic lymphocytic leukemia (CLL) and the New Zealand Black (NZB) murine model of CLL, decreased levels of microRNAs miR-15a/16 play an important role in the disease. Here we investigate the effects of this microRNA on early steps of B cell development and the capacity of miR-15a-defi...

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Publicat a:Oncotarget
Autors principals: Underbayev, Chingiz, Kasar, Siddha, Ruezinsky, William, Degheidy, Heba, Schneider, Joel Solomon, Marti, Gerald, Bauer, Steven R., Fraidenraich, Diego, Lightfoote, Marilyn M., Parashar, Vijay, Raveche, Elizabeth, Batish, Mona
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308631/
https://ncbi.nlm.nih.gov/pubmed/27533467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11290
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