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A New Role for ERα: Silencing via DNA methylation of Basal, Stem Cell, and EMT Genes

Resistance to hormonal therapies is a major clinical problem in the treatment of estrogen receptor-α (ERα) positive breast cancers. Epigenetic marks namely DNA methylation of cytosine at specific CpG sites (5mCpG) are frequently associated with ERα-positive status in human breast cancers. Therefore,...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Ariazi, Eric A., Taylor, John C., Black, Michael A., Nicolas, Emmanuelle, Slifker, Michael J., Azzam, Diana J., Boyd, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308451/
https://ncbi.nlm.nih.gov/pubmed/28108626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0283
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