Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties

The epithelial-mesenchymal transition (EMT) imparts metastatic competence on otherwise non-metastatic cancer cells through decreased inter-cellular adhesions, increased migratory capacity, stem cell properties and anoikis and chemotherapy resistance. In this study, we profiled changes in microRNA ex...

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Detalhes bibliográficos
Main Authors: Taube, Joseph H., Malouf, Gabriel G., Lu, Emily, Sphyris, Nathalie, Vijay, Vidya, Ramachandran, Priyanka P., Ueno, Katumasa R., Gaur, Sanchaika, Nicoloso, Milena S., Rossi, Simona, Herschkowitz, Jason I., Rosen, Jeffrey M., Issa, Jean-Pierre J., Calin, George A., Chang, Jeffrey T., Mani, Sendurai A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3776231/
https://ncbi.nlm.nih.gov/pubmed/24045437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02687
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