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Effects of GPI-anchored TNAP on the dynamic structure of model membranes

Tissue-nonspecific alkaline phosphatase (TNAP) plays a crucial role during skeletal mineralization, and TNAP deficiency leads to the soft bone disease hypophosphatasia. TNAP is anchored to the external surface of the plasma membranes by means of a GPI (glycosylphosphatidylinositol) anchor. Membrane-...

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Detalles Bibliográficos
Publicado en:Phys Chem Chem Phys
Main Authors: Garcia, A. F., Simão, A. M. S., Bolean, M, Hoylaerts, M. F., Millán, J. L., Ciancaglini, P, Costa-Filho, A. J.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5308125/
https://ncbi.nlm.nih.gov/pubmed/26389140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cp02377g
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