Structure, Dynamics, and Interactions of GPI-Anchored Human Glypican-1 with Heparan Sulfates in a Membrane

Glypican-1 and its heparan sulfate (HS) chains play important roles in modulating many biological processes including growth factor signaling. Glypican-1 is bound to a membrane surface via a glycosylphosphatidylinositol (GPI)-anchor. In this study, we used all-atom molecular modeling and simulation...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Dong, Chuqiao, Choi, Yeol Kyo, Lee, Jumin, Zhang, X Frank, Honerkamp-Smith, Aurelia, Widmalm, Göran, Lowe-Krentz, Linda J, Im, Wonpil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Regular Manuscripts
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176774/
https://ncbi.nlm.nih.gov/pubmed/33021626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwaa092
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