Screening of breast cancer stem cell inhibitors using a protein kinase inhibitor library

BACKGROUND: Cancer stem cells (CSCs), a subpopulation in tumors, are known to cause drug resistance, tumor recurrence and metastasis. Based on the characteristic formation of mammospheres in in vitro conditions, the mammosphere formation assay has become an essential tool for quantifying CSC activit...

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Опубликовано в: :Cancer Cell Int
Главные авторы: Choi, Hack Sun, Kim, Dal-Ah, Chung, Heesung, Park, In Ho, Kim, Bo Hye, Oh, Eok-Soo, Kang, Duk-Hee
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2017
Предметы:
Primary Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307923/
https://ncbi.nlm.nih.gov/pubmed/28289331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-017-0392-z
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