Comparative Pharmacokinetic Profiles of Three Protoberberine-type Alkaloids from Raw and Bile-processed Rhizoma coptidis in Heat Syndrome Rats

BACKGROUND: The Bile-processed Rhizoma coptidis (BRC), which has a colder drug property than Rhizoma coptidis (RC), is widely used for the treatment of heat syndrome. We compared the pharmacokinetics of the protoberberine-type alkaloids in BRC and RC in rats with heat syndrome to elucidate the bile-...

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Bibliographic Details
Published in:Pharmacogn Mag
Main Authors: Zi-min, Yuan, Yue, Chen, Hui, Gao, Jia, Lv, Gui-rong, Chen, Wang, Jing
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2017
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307914/
https://ncbi.nlm.nih.gov/pubmed/28216883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0973-1296.197632
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