Pharmacokinetics of Two Alkaloids after Oral Administration of Rhizoma Coptidis Extract in Normal Rats and Irritable Bowel Syndrome Rats

A comparative pharmacokinetic study of berberine and palmatine after oral administration of Rhizoma Coptidis extract (96 mg/kg, containing berberine 22 mg/kg and palmatine 5 mg/kg based on body weight) was performed in normal and postinflammation irritable bowel syndrome (PI-IBS) rats, induced by in...

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Detalhes bibliográficos
Main Authors: Gong, Zipeng, Chen, Ying, Zhang, Ruijie, Wang, Yinghan, Yang, Qing, Guo, Yan, Weng, Xiaogang, Gao, Shuangrong, Wang, Hailin, Zhu, Xiaoxin, Dong, Yu, Li, Yujie, Wang, Yajie
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163303/
https://ncbi.nlm.nih.gov/pubmed/25309613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/845048
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