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A novel point mutation in RpoB improves osmotolerance and succinic acid production in Escherichia coli
BACKGROUND: Escherichia coli suffer from osmotic stress during succinic acid (SA) production, which reduces the performance of this microbial factory. RESULTS: Here, we report that a point mutation leading to a single amino acid change (D654Y) within the β-subunit of DNA-dependent RNA polymerase (Rp...
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| Veröffentlicht in: | BMC Biotechnol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5307762/ https://ncbi.nlm.nih.gov/pubmed/28193207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0337-6 |
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