ATF5 regulates β-cell survival during stress

The stress response and cell survival are necessary for normal pancreatic β-cell function, glucose homeostasis, and prevention of diabetes. The homeodomain transcription factor and human diabetes gene pancreas/duodenum homeobox protein 1 (Pdx1) regulates β-cell survival and endoplasmic reticulum str...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Juliana, Christine A., Yang, Juxiang, Rozo, Andrea V., Good, Austin, Groff, David N., Wang, Shu-Zong, Green, Michael R., Stoffers, Doris A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5307469/
https://ncbi.nlm.nih.gov/pubmed/28115692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620705114
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