Effect of opicapone multiple‐dose regimens on levodopa pharmacokinetics

AIMS: To compare the levodopa/carbidopa (LC) and levodopa/benserazide (LB) pharmacokinetic profiles following repeated doses of opicapone (OPC) administered apart from levodopa. METHODS: Two randomized, double blind, sex‐balanced, placebo‐controlled studies in four groups of 12 or 18 healthy subject...

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書目詳細資料
發表在:Br J Clin Pharmacol
Main Authors: Rocha, José‐Francisco, Sicard, Éric, Fauchoux, Nicolas, Falcão, Amílcar, Santos, Ana, Loureiro, Ana I., Pinto, Roberto, Bonifácio, Maria João, Nunes, Teresa, Almeida, Luís, Soares‐da‐Silva, Patrício
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Pharmacokinetic Dynamic Relationships
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306497/
https://ncbi.nlm.nih.gov/pubmed/27763682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13156
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