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Biomarker‐guided clinical development of the first‐in‐class anti‐inflammatory FPR2/ALX agonist ACT‐389949
AIMS: The main objectives of these two phase I studies were to investigate safety and tolerability as well as the pharmacokinetic/pharmacodynamic profile of the novel potent and selective formyl peptide receptor type 2 (FPR2)/Lipoxin A(4) receptor (ALX) agonist ACT‐389949. A challenge model was used...
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| Publicado en: | Br J Clin Pharmacol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5306489/ https://ncbi.nlm.nih.gov/pubmed/27730665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13149 |
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