Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder

Disruption of the human SHANK3 gene can cause several neuropsychiatric disease entities including Phelan-McDermid syndrome, autism spectrum disorder (ASD), and intellectual disability. Although, a wide array of neurobiological studies strongly supports a major role for SHANK3 in organizing the post-...

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Dettagli Bibliografici
Pubblicato in:Front Mol Neurosci
Autori principali: Reim, Dominik, Distler, Ute, Halbedl, Sonja, Verpelli, Chiara, Sala, Carlo, Bockmann, Juergen, Tenzer, Stefan, Boeckers, Tobias M., Schmeisser, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306440/
https://ncbi.nlm.nih.gov/pubmed/28261056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00026
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