Activation of the medial preoptic area (MPOA) ameliorates loss of maternal behavior in a Shank2 mouse model for autism

Impairments in social relationships and awareness are features observed in autism spectrum disorders (ASDs). However, the underlying mechanisms remain poorly understood. Shank2 is a high‐confidence ASD candidate gene and localizes primarily to postsynaptic densities (PSDs) of excitatory synapses in...

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Pubblicato in:EMBO J
Autori principali: Grabrucker, Stefanie, Pagano, Jessica, Schweizer, Johanna, Urrutia‐Ruiz, Carolina, Schön, Michael, Thome, Kevin, Ehret, Günter, Grabrucker, Andreas M, Zhang, Rong, Hengerer, Bastian, Bockmann, Jürgen, Verpelli, Chiara, Sala, Carlo, Boeckers, Tobias M
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7917557/
https://ncbi.nlm.nih.gov/pubmed/33491217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019104267
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