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Mechanism of Action of Prolyl Oligopeptidase (PREP) in Degenerative Brain Diseases: Has Peptidase Activity Only a Modulatory Role on the Interactions of PREP with Proteins?

In the aging brain, the correct balance of neural transmission and its regulation is of particular significance, and neuropeptides have a significant role. Prolyl oligopeptidase (PREP) is a protein highly expressed in brain, and evidence indicates that it is related to aging and in neurodegenration....

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Detaylı Bibliyografya
Yayımlandı:Front Aging Neurosci
Asıl Yazarlar: Männistö, Pekka T., García-Horsman, J. Arturo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5306367/
https://ncbi.nlm.nih.gov/pubmed/28261087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2017.00027
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