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Fidgetin regulates cultured astrocyte migration by severing tyrosinated microtubules at the leading edge

Microtubule (MT) organization is essential for many cellular events, including mitosis, migration, and cell polarity. Fidgetin (Fign), an ATP-dependent, MT-severing protein, contributes to the regulation of MT configuration by cutting and trimming MT polymers. Functions of Fign have been indicated i...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Hu, Zunlu, Feng, Jie, Bo, Weijuan, Wu, Ronghua, Dong, Zhangji, Liu, Yan, Qiang, Liang, Liu, Mei
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305261/
https://ncbi.nlm.nih.gov/pubmed/27974640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-09-0628
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