Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice

Estrogen, a natural immunomodulator, regulates the development and function of diverse immune cell types. There is now renewed attention on neutrophils and neutrophil serine proteases (NSPs) such as neutrophil elastase (NE), proteinase 3 (PR3), and cathepsin G (CG) in inflammation and autoimmunity....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dai, Rujuan, Cowan, Catharine, Heid, Bettina, Khan, Deena, Liang, Zhihong, Pham, Christine T. N., Ahmed, S. Ansar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5305105/
https://ncbi.nlm.nih.gov/pubmed/28192517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172105
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