Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms

Heteroaryldihydropyrimidine (HAP) and sulfamoylbenzamide (SBA) are promising non-nucleos(t)ide HBV replication inhibitors. HAPs are known to promote core protein mis-assembly, but the molecular mechanism of abnormal assembly is still elusive. Likewise, the assembly status of core protein induced by...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhou, Zheng, Hu, Taishan, Zhou, Xue, Wildum, Steffen, Garcia-Alcalde, Fernando, Xu, Zhiheng, Wu, Daitze, Mao, Yi, Tian, Xiaojun, Zhou, Yuan, Shen, Fang, Zhang, Zhisen, Tang, Guozhi, Najera, Isabel, Yang, Guang, Shen, Hong C., Young, John A. T., Qin, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304331/
https://ncbi.nlm.nih.gov/pubmed/28205569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42374
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