Activating Killer Immunoglobulin Receptors and HLA-C: a successful combination providing HIV-1 control

Several studies demonstrated a relevant role of polymorphisms located within the HLA-B and -C loci and the Killer Immunoglobulin Receptors (KIRs) 3DL1 and 3DS1 in controlling HIV-1 replication. KIRs are regulatory receptors expressed at the surface of NK and CD8+ T-cells that specifically bind HLA-A...

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Publicado no:Sci Rep
Main Authors: Malnati, Mauro S., Ugolotti, Elisabetta, Monti, Maria Cristina, Battista, Davide De, Vanni, Irene, Bordo, Domenico, Sironi, Francesca, Larghero, Patrizia, Marco, Eddi Di, Biswas, Priscilla, Poli, Guido, Vicenzi, Elisa, Riva, Agostino, Tarkowski, Maciej, Tambussi, Giuseppe, Nozza, Silvia, Tripodi, Gino, Marras, Francesco, Maria, Andrea De, Pistorio, Angela, Biassoni, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304173/
https://ncbi.nlm.nih.gov/pubmed/28211903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42470
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