Envelope-Dependent Restriction of Human Immunodeficiency Virus Type 1 Spreading in CD4(+) T Lymphocytes: R5 but Not X4 Viruses Replicate in the Absence of T-Cell Receptor Restimulation

The human immunodeficiency virus (HIV) replicates in activated CD4(+) T lymphocytes. However, only CD4(+) Th2 and Th0, but not Th1, CD4(+) T-cell clones have been reported to efficiently support HIV-1 replication. This dichotomous pattern was further investigated in the present study in Th1, Th2, or...

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Main Authors: Vicenzi, Elisa, Bordignon, Paola Panina, Biswas, Priscilla, Brambilla, Andrea, Bovolenta, Chiara, Cota, Manuela, Sinigaglia, Francesco, Poli, Guido
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC104278/
https://ncbi.nlm.nih.gov/pubmed/10438841
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