Envelope-Dependent Restriction of Human Immunodeficiency Virus Type 1 Spreading in CD4(+) T Lymphocytes: R5 but Not X4 Viruses Replicate in the Absence of T-Cell Receptor Restimulation

The human immunodeficiency virus (HIV) replicates in activated CD4(+) T lymphocytes. However, only CD4(+) Th2 and Th0, but not Th1, CD4(+) T-cell clones have been reported to efficiently support HIV-1 replication. This dichotomous pattern was further investigated in the present study in Th1, Th2, or...

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Vydáno v:	J Virol
Hlavní autoři:	Vicenzi, Elisa, Bordignon, Paola Panina, Biswas, Priscilla, Brambilla, Andrea, Bovolenta, Chiara, Cota, Manuela, Sinigaglia, Francesco, Poli, Guido
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Replication
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104278/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438841/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7515-7523.1999
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