Transient Dysregulation of Dopamine Signaling in a Developing Drosophila Arousal Circuit Permanently Impairs Behavioral Responsiveness in Adults

The dopamine ontogeny hypothesis for schizophrenia proposes that transient dysregulation of the dopaminergic system during brain development increases the likelihood of this disorder in adulthood. To test this hypothesis in a high-throughput animal model, we have transiently manipulated dopamine sig...

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Publicat a:Front Psychiatry
Autors principals: Ferguson, Lachlan, Petty, Alice, Rohrscheib, Chelsie, Troup, Michael, Kirszenblat, Leonie, Eyles, Darryl W., van Swinderen, Bruno
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Psychiatry
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5304146/
https://ncbi.nlm.nih.gov/pubmed/28243212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2017.00022
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