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Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer

Resistance to 5-Fluorouracil (5-FU) is a major obstacle to the successful treatment of colorectal cancer (CRC) and posed an increased risk of recurrence. DNA methylation has been suggested as one of the underlying mechanisms for recurrent disease and its contribution to the development of drug resis...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Baharudin, Rashidah, Ab Mutalib, Nurul-Syakima, Othman, Sri N., Sagap, Ismail, Rose, Isa M., Mohd Mokhtar, Norfilza, Jamal, Rahman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303736/
https://ncbi.nlm.nih.gov/pubmed/28243201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00047
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