Identification of Predictive DNA Methylation Biomarkers for Chemotherapy Response in Colorectal Cancer

Resistance to 5-Fluorouracil (5-FU) is a major obstacle to the successful treatment of colorectal cancer (CRC) and posed an increased risk of recurrence. DNA methylation has been suggested as one of the underlying mechanisms for recurrent disease and its contribution to the development of drug resis...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Baharudin, Rashidah, Ab Mutalib, Nurul-Syakima, Othman, Sri N., Sagap, Ismail, Rose, Isa M., Mohd Mokhtar, Norfilza, Jamal, Rahman
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303736/
https://ncbi.nlm.nih.gov/pubmed/28243201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00047
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