High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation

Stem and progenitor cells that exhibit significant regenerative potential and critical roles in cancer initiation and progression remain difficult to characterize. Cell fates are determined by reciprocal signaling between the cell microenvironment and the nucleus; hence parameters derived from nucle...

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Vydáno v:Exp Cell Res
Hlavní autoři: Vega, Sebastián L., Liu, Er, Arvind, Varun, Bushman, Jared, Sung, Hak-Joon, Becker, Matthew L., Lelièvre, Sophie, Kohn, Joachim, Vidi, Pierre-Alexandre, Moghe, Prabhas V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303152/
https://ncbi.nlm.nih.gov/pubmed/28034673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.12.018
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