High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation

Stem and progenitor cells that exhibit significant regenerative potential and critical roles in cancer initiation and progression remain difficult to characterize. Cell fates are determined by reciprocal signaling between the cell microenvironment and the nucleus; hence parameters derived from nucle...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Cell Res
Main Authors: Vega, Sebastián L., Liu, Er, Arvind, Varun, Bushman, Jared, Sung, Hak-Joon, Becker, Matthew L., Lelièvre, Sophie, Kohn, Joachim, Vidi, Pierre-Alexandre, Moghe, Prabhas V.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303152/
https://ncbi.nlm.nih.gov/pubmed/28034673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2016.12.018
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