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Characterization of HCV NS3 Protease Variants in HCV/HIV Coinfected Patients by Ultra-deep Sequence Analysis: Relationship with Hepatic Fibrosis

BACKGROUND: Treatment of HCV/HIV coinfection is now largely based upon utilization of direct acting agents. Pre-treatment viral resistant-associated variants (RAVs) and host liver condition may affect the sustained virological response. In this study, we explored relative prevalence of protease resi...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: Abdel-hameed, Enass A., Rouster, Susan D., Zhang, Xiang, Chen, Jing, Medvedovic, Mario, Goodman, Zachary D., Sherman, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5303138/
https://ncbi.nlm.nih.gov/pubmed/27898525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001256
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