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Evaluating the Role of Cellular Immune Responses in the Emergence of HCV NS3 Resistance Mutations During Protease Inhibitor Therapy

The efficacy of protease inhibitor drugs in hepatitis C virus (HCV) treatment is limited by the selection and expansion of drug-resistant mutations. HCV replication is error-prone and genetic variability within the dominant epitopes ensures its persistence. The aims of this study are to evaluate the...

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Dettagli Bibliografici
Pubblicato in:Viral Immunol
Autori principali: Abdel-hameed, Enass A., Rouster, Susan D., Ji, Hong, Ulm, Ashley, Hetta, Helal F., Anwar, Nadeem, Sherman, Kenneth E., Shata, Mohamed Tarek M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860622/
https://ncbi.nlm.nih.gov/pubmed/26885675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2015.0093
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