Pregnane X-receptor promotes stem cell-mediated colon cancer relapse

Colorectal cancer lethality usually results from post-treatment relapse in the majority of stage II-IV patients, due to the enhanced resistance of Cancer Stem Cells (CSCs). Here, we show that the nuclear receptor Pregnane X Receptor (PXR, NR1I2), behaves as a key driver of CSC-mediated tumor recurre...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Oncotarget
Главные авторы: Planque, Chris, Rajabi, Fatemeh, Grillet, Fanny, Finetti, Pascal, Bertucci, François, Gironella, Meritxell, Lozano, Juan José, Beucher, Bertrand, Giraud, Julie, Garambois, Véronique, Vincent, Charles, Brown, Daniel, Caillo, Ludovic, Kantar, Jovana, Pelegrin, André, Prudhomme, Michel, Ripoche, Jérémie, Bourgaux, Jean François, Ginestier, Christophe, Castells, Antoni, Hollande, Frédéric, Pannequin, Julie, Pascussi, Jean Marc
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302934/
https://ncbi.nlm.nih.gov/pubmed/27448961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10646
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы