Pregnane X-receptor promotes stem cell-mediated colon cancer relapse

Colorectal cancer lethality usually results from post-treatment relapse in the majority of stage II-IV patients, due to the enhanced resistance of Cancer Stem Cells (CSCs). Here, we show that the nuclear receptor Pregnane X Receptor (PXR, NR1I2), behaves as a key driver of CSC-mediated tumor recurre...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Planque, Chris, Rajabi, Fatemeh, Grillet, Fanny, Finetti, Pascal, Bertucci, François, Gironella, Meritxell, Lozano, Juan José, Beucher, Bertrand, Giraud, Julie, Garambois, Véronique, Vincent, Charles, Brown, Daniel, Caillo, Ludovic, Kantar, Jovana, Pelegrin, André, Prudhomme, Michel, Ripoche, Jérémie, Bourgaux, Jean François, Ginestier, Christophe, Castells, Antoni, Hollande, Frédéric, Pannequin, Julie, Pascussi, Jean Marc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302934/
https://ncbi.nlm.nih.gov/pubmed/27448961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10646
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