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Inhibition of prolyl 4-hydroxylase decreases muscle fibrosis following chronic rotator cuff tear

OBJECTIVES: Rotator cuff tears are among the most frequent upper extremity injuries. Current treatment strategies do not address the poor quality of the muscle and tendon following chronic rotator cuff tears. Hypoxia-inducible factor-1 alpha (HIF-1α) is a transcription factor that activates many gen...

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Bibliografiske detaljer
Udgivet i:Bone Joint Res
Main Authors: Gumucio, J. P., Flood, M. D., Bedi, A., Kramer, H. F., Russell, A. J., Mendias, C. L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301902/
https://ncbi.nlm.nih.gov/pubmed/28108482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.61.BJR-2016-0232.R1
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