GlcNAc6ST-1 regulates sulfation of N-glycans and myelination in the peripheral nervous system

Highly specialized glial cells wrap axons with a multilayered myelin membrane in vertebrates. Myelin serves essential roles in the functioning of the nervous system. Axonal degeneration is the major cause of permanent neurological disability in primary myelin diseases. Many glycoproteins have been i...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Yoshimura, Takeshi, Hayashi, Akiko, Handa-Narumi, Mai, Yagi, Hirokazu, Ohno, Nobuhiko, Koike, Takako, Yamaguchi, Yoshihide, Uchimura, Kenji, Kadomatsu, Kenji, Sedzik, Jan, Kitamura, Kunio, Kato, Koichi, Trapp, Bruce D., Baba, Hiroko, Ikenaka, Kazuhiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5301494/
https://ncbi.nlm.nih.gov/pubmed/28186137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42257
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